IONAMIN 30mg. Tablets.

For the short-term treatment of obesity, used as an adjunct to behavior modifications including dietary modification and appropriate exercise.
Oral dosage (phentermine hydrochloride 15 mg or more per oral capsule or tablet; e.g., Adipex-P)
Adults and Adolescents 17 years and older
15 to 37.5 mg PO once per day as a single dose every morning before breakfast or approximately 2 hours after breakfast. Some tablets with a score may be divided, with 18.75 mg (half-tablet) given in morning and the other half-tablet later in the day (but not in late evening), if needed. For some patients 18.75 mg PO once daily is sufficient. Geriatric patients may require lower dosage. Phentermine is indicated for obese patients with a BMI 30 kg/m2 or more or in patients with a BMI 27 kg/m2 or more in the presence of other risk factors (e.g., controlled hypertension, diabetes mellitus, or dyslipidemia). The equation for calculating BMI is weight in kilograms divided by height in m2.

Oral dosage (phentermine 8 mg tablet; e.g., Lomaira)
Adults and Adolescents 17 years and older
8 mg PO 3 times per day, 30 minutes before meals. Because geriatric patients have an increased risk of hepatic, renal, or cardiac dysfunction, dosing selection in geriatrics should be cautious, usually starting at the low end of the dosing range. One-half of the usual dose (i.e., 4 mg PO 3 times/day) may be used for patients not requiring the full dose. The regimen should be individualized to obtain an adequate response with the lowest effective dose. Late evening dosing should be avoided due to the potential for insomnia. Phentermine is indicated for obese patients with a BMI 30 kg/m2 or more or in patients with a BMI 27 kg/m2 or more in the presence of other risk factors (e.g., controlled hypertension, diabetes mellitus, or dyslipidemia). The equation for calculating BMI is weight in kilograms divided by height in m2.

Adults
37.5 mg/day PO.

Elderly
37.5 mg/day PO. May require reduced dosage compared to younger adults.

Adolescents
> 16 years: 37.5 mg/day PO.
<= 16 years: Safety and efficacy have not been established.

Children
Safety and efficacy have not been established.

Hepatic Impairment
The effects of hepatic impairment on phentermine and its metabolites are unknown.

Renal Impairment
Use with caution. Specific guidelines for dosage adjustments in renal impairment are not available. Based on the reported excretion of phentermine in urine, exposure increases can be expected in patients with renal impairment.

Oral Administration
Phentermine hydrochloride oral capsules or tablets (Adipex-P or equivalent 15 mg to 37.5 mg products):
The usual dose is administered daily before breakfast or 1 to 2 hours after breakfast.
Tablets may contain a score to allow daily dose to be divided in half and administered before meals or 1 to 2 hours after meals.
Avoid late evening administration because of the possibility of insomnia.

Phentermine hydrochloride oral tablets (Lomaira 8 mg tablet or an equivalent 8 mg product):
The usual dose is administered three times per day, 30 minutes before meals.
The tablets are scored for administration of one-half of the usual dosage for patients not requiring the full dose.
Avoid late evening administration because of the possibility of insomnia.

Generic:
– Protect from moisture
– Store at controlled room temperature (between 68 and 77 degrees F)
Adipex-P:
– Store at controlled room temperature (between 68 and 77 degrees F)
Atti-Plex P :
– Store at controlled room temperature (between 68 and 77 degrees F)
Atti-Plex P Spansule :
– Store at controlled room temperature (between 68 and 77 degrees F)
Fastin:
– Protect from moisture
– Store at controlled room temperature (between 68 and 77 degrees F)
Ionamin:
– Store at 77 degrees F; excursions permitted to 59-86 degrees F
Lomaira :
– Store at controlled room temperature (between 68 and 77 degrees F)
Pro-Fast:
– Discard product if it contains particulate matter, is cloudy, or discolored
– Protect from light
– Store at controlled room temperature (between 68 and 77 degrees F)
– Store in original container
Suprenza:
– Store at controlled room temperature (between 68 and 77 degrees F)